FaSSIF-V2 Tampon Concentrate

FaSSIF-V2 Tampon Concentrate

Biorelevant FaSSIF-V2 is a dissolution medium that simulates human fasted state intestinal fluid.

Although FaSSIF-V2 was released after FaSSIF, it is not superior to the original medium. It contains the same physiological surfactants as FaSSIF but with a slightly different bile salt: lecithin ratio.

If you are new to using biorelevant media, we recommend starting with our best-selling FaSSIF/FeSSIF/FaSSGF, which allows you to produce three different biorelevant media from the same powder (this cannot be done with FaSSIF-V2). However, if you are developing an oral drug, FaSSIF-V2 is still an extremely useful test medium:

• As with FaSSIF, it can help you gain in vitro insights into drug solubility and dissolution in the small intestine before a meal.

• FaSSIF-V2 is identified as one of the recommended biorelevant media for testing drug solubility in human fasted state simulated intestinal fluid in the recently introduced "USP Chapter <1236> Solubility Measurements."

• Ideal for use in USP1 or USP2 dissolution apparatus (we recommend 900 mL FaSSIF-V2 per vessel).

• Drug analysis can be performed using HPLC.

• Simple and quick preparation method.

Obtain customized instructions from our Media Preparation Tool, explaining how to create different FaSSIF-V2 volumes (see above).